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The Role of the Autonomic Nervous System in Atrial Fibrillation

The Role of the Autonomic Nervous System in Atrial Fibrillation
December 4, 2018ahsanNews

The Role of the Autonomic Nervous System in Atrial Fibrillation.

Why does a bloated stomach cause AF?

Role of the Autonomic Nervous System in Atrial Fibrillation

Dr Lim was invited to speak on the 28th Nov 2018 at the London Cardiovascular Society Meeting held at the Medical Society of London, on Chandos Street, in Central London.

 

In his lecture, Dr Lim discussed some of the principles around the role of the autonomic nervous system in atrial fibrillation – discussing in particular his research leading to a PhD at Imperial College London where he performed studies in which performing high frequency stimulation of the cardiac nervous system (the autonomic nervous system of the heart) through electrodes places within the human atrium.

 

Some of this work helps explain why AF can be caused by certain autonomic triggers, including:

  • A large meal
  • Alcohol
  • AF occurring exclusively at night
  • Occurring at rest several hours following exercise

 

The figure below illustrates how there is a complex and intricate network of nerves that supply the heart (and gut) which arise from the brain and eventually reach the heart. These nerves carry both sensory (is sensing) and motor (i.e. action or doing) traffic.

For example a strong surge in a particular nervous system (the sympathetic  nervous system governing the flight or fright response) may lead to an increased heart rate and strength of contraction. Conversely, stimulation of the vagus nerve (which governs resting and digesting), may lead to a significant slowing in heart rate, and can sometimes trigger atrial fibrillation.

bloated stomach cause AF

The role of the autonomic nervous system in AF was elegantly demonstrated by Gordon Moe, in the 1950s who demonstrated that for AF to persist in dogs, the autonomic nervous system (vagal nerve) needed to be continuously stimulated, as show in the figure below.

Moe published this work in the American Heart Journal in 1959, and this seminal piece of work is still relevant today as it was almost 60 years ago!

autonomic nervous system

If AF is triggered clearly by autonomic influences, there may be appropriate drugs, or catheter ablation strategies to help improve symptoms.

 

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Dr Lim is an experienced Consultant Cardiologist and Electrophysiologist. He is the clinical lead for the nationally-renowned Imperial Syncope Diagnostic Service based at Hammersmith Hospital London.

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